401) |
Kim Y.J., Kim Y.A., Yokozawa T.: Pycnogenol modulates apoptosis by suppressing oxidative stress and inflammation in high glucose-treated renal tubular cells. Food Chem. Toxicol., 49, 2196-2201 (2011). |
402) |
Okamoto T., Park C.H., Noh J.S., Toriizuka K., Sei Y., Park J.C., Yokozawa T.: Hepato-/reno-protective activity of Chinese prescription Kangen-karyu through inhibition of AGE formation and fibrosis-related protein expression in type 2 diabetes. J. Pharm. Pharmacol., 63, 952-959 (2011). |
403) |
Park C.H., Noh J.S., Kim J.H., Tanaka T., Zhao Q., Matsumoto K., Shibahara N., Yokozawa T.: Evaluation of Morroniside, Iridoid Glycoside from Corni Fructus, on Diabetes-Induced Alterations such as Oxidative Stress, Inflammation, and Apoptosis in the Liver of Type 2 Diabetic db/db Mice. Biol. Pharm. Bull., 34, 1559-1565 (2011). |
404) |
Park C.H., Tanaka T., Kim J.H., Cho E.J., Park J.C., Shibahara N., Yokozawa T.: Hepato-protective effects of loganin, iridoid glycoside from Corni Fructus, against hyperglycemia-activated signaling pathway in liver of type 2 diabetic db/db mice. Toxicology, 290, 14-21 (2011). |
405) |
Zhao Q., Yokozawa T., Tsuneyama K., Tanaka K., Miyata T., Shibahara N., Matsumoto K.: Chotosan (Diaoteng San)-induced improvement of cognitive deficits in senescence-accelerated mouse (SAMP8) involves the amelioration of angiogenic/neurotrophic factors and neuroplasticity systems in the brain. Chin. Med., 6:33 (on line), 1-18 (2011). |
406) |
Zhao Q., Matsumoto K., Tsuneyama K., Tanaka K., Li F., Shibahara N., Miyata T., Yokozawa T.: Diabetes-Induced Central Cholinergic Neuronal Loss and Cognitive Deficit Are Attenuated by Tacrine and a Chinese Herbal Prescription, Kangen-Karyu: Elucidation in Type 2 Diabetes db/db Mice. J. Pharmacol. Sci., 117, 230-242 (2011). |
407) |
Park C.H., Tanaka T., Cho E.J., Park J.C., Shibahara N., Yokozawa T.: Glycerol-Induced Renal Damage Improved by 7-O-Galloyl-D-sedoheptulose Treatment through Attenuating Oxidative Stress. Biol. Pharm. Bull., 35, 34-41 (2012). |
408) |
Park C.H., Tanaka T., Kim H.Y., Park J.C., Yokozawa T.: Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging. Evid. Based Complement. Alternat. Med., 2012, Article ID 418953, 7 pages (2012). |
409) |
Park C.H., Noh J.S., Okamoto T., Park J.C., Yokozawa T.: Evaluation of Effects of Chinese Prescription Kangen-karyu on Diabetes-Induced Alterations such as Oxidative Stress and Apoptosis in the Liver of Type 2 Diabetic db/db Mice. Evid. Based Complement. Alternat. Med., 2012, Article ID 143489, 12 pages (2012). |
410) |
Noh J.S., Park C.H., Tanaka T., Yokozawa T.: 7-O-Galloyl-D-sedoheptulose Attenuates Oxidative Stress-Induced Diabetic Injury via Decreasing Expression of Nuclear Factor-κB- and Apoptosis-Related Protein in the Liver. Biol. Pharm. Bull., 35, 950-956 (2012). |
411) |
Park C.H., Noh J.S., Tanaka T., Yokozawa T.: 7-O-Galloyl-D-sedoheptulose ameliorates renal damage triggered by reactive oxygen species-sensitive pathway of inflammation and apoptosis. J. Pharm. Pharmacol., 64, 1730-1740 (2012). |
412) |
Zhao Q., Niu Y., Matsumoto K., Tsuneyama K., Tanaka K., Miyata T., Yokozawa T.: Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain. BMC Complement. Altern. Med., 12, 188 (2012). |
413) |
Park C.H., Lee S.L., Okamoto T., Tanaka T., Yokozawa T.: Rokumi-jio-gan-Containing Prescriptions Attenuate Oxidative Stress, Inflammation, and Apoptosis in the Remnant Kidney. Evid. Based Complement. Alternat. Med., 2012, Article ID 587902, 15 pages (2012). |
414) |
Ienaga K., Park C.H., Yokozawa T.: Protective effect of an intrinsic antioxidant, HMH (5-hydroxy-1-methylhydantoin; NZ-419), against cellular damage of kidney tubules. Exp. Toxic. Pathol., 65, 559-566 (2013). |
415) |
Park C.H., Tanaka T., Yokozawa T.: Anti-diabetic Action of 7-O-Galloyl-D-sedoheptulose, a Polyphenol from Corni Fructus, through Ameliorating Inflammation and Inflammation-Related Oxidative Stress in the Pancreas of Type 2 Diabetics. Biol. Pharm. Bull., 36, 723-732 (2013). |
416) |
Park C.H., Rhyu D.Y., Sharma B.R., Yokozawa T.: Inhibition of preadipocyte differentiation and lipid accumulation by 7-O-galloyl-D-sedoheptulose treatment in 3T3-L1 adipocytes. Biomed. Prevent. Nutr., 3, 319-324 (2013). |
417) |
Park C.H., Tanaka T., Yokozawa T.: Evaluation of 7-O-galloyl-D-sedoheptulose, isolated from Corni Fructus, in the adipose tissue of type 2 diabetic db/db mice. Fitoterapia, 89, 131-142 (2013). |
418) |
Park C.H., Lee S.L., Noh J.S., Yokozawa T.: Rokumi-jio-gan-containing prescriptions regulate oxidative stress through improving dyslipidemia in a subtotal nephrectomized rat model. J. Ethnopharmacol., 148, 449-458 (2013). |
419) |
Yokozawa T., Satoh A., Kim Y.J.: Modulation of Oxidative Stress by Proanthocyanidin in H2O2-Exposed Human Diploid Fibroblast Cells. Biosci. Biotechnol. Biochem., 77, 2056-2060 (2013). |
420) |
Park C.H., Kim D.H., Park M.H., Kim M.K., Kim N.D., Kim C.M., Tanaka T., Yokozawa T., Chung H.Y., Moon H.R.: Chinese Prescription Kangen-karyu and Salviae Miltiorrhizae Radix Improve Age-Related Oxidative Stress and Inflammatory Response through the PI3K/Akt or MAPK Pathways. Am. J. Chin. Med., 42, 987-1005 (2014). |
421) |
Park C.H., Rhyu D.Y., Noh J.S., Park C.M., Yokozawa T.: Effectiveness of Chinese prescription Kangen-karyu for dyslipidemia, using 3T3-L1 adipocytes and type 2 diabetic mice. Drug Discov. Ther., 8, 121-131 (2014). |
422) |
Sharma B.R., Kim M.S., Yokozawa T., Rhyu D.Y.: Anti-oxidant and anti-diabetic activities of Lespedeza cuneata water extract. J. Med. Plants Res., 8, 935-941 (2014). |
423) |
Park C.H., Yokozawa T., Noh J.S.: Oligonol, a Low-Molecular-Weight Polyphenol Derived from Lychee Fruit, Attenuates Diabetes-Induced Renal Damage through the Advanced Glycation End Product-Related Pathway in db/db Mice. J. Nutr., 144, 1150-1157 (2014). |
424) |
Jung Y.R., Kim D.H., Kim S.R., An H.J., Lee E.K., Tanaka T., Kim N.D., Yokozawa T., Park J.N., Chung H.Y.: Anti-Wrinkle Effect of Magnesium Lithospermate B from Salvia miltiorrhiza BUNGE: Inhibition of MMPs via NF-κB Signaling. PLoS ONE, 9, e102689 (2014). |
425) |
Choi Y.Y., Maeda T., Fujii H., Yokozawa T., Kim H.Y., Cho E.J., Shibamoto T.: Oligonol improves memory and cognition under an amyloid β25-35-induced Alzheimer’s mouse model. Nutr. Res., 34, 595-603 (2014). |
426) |
Sung B., Park S., Ha Y.M., Kim D.H., Park C.H., Jung K.J., Kim M.S., Kim Y.J., Kim M.K., Moon J.O., Yokozawa T., Kim N.D., Yu B.P., Chung H.Y.: Salicylideneamino-2-thiophenol modulates nuclear factor-κB through redox regulation during the aging process. Geriatr. Gerontol. Int., 15, 211-219 (2015). |
427) |
Park C.H., Xu F.H., Roh S.S., Song Y.O., Uebaba K., Noh J.S., Yokozawa T.: Astaxanthin and Corni Fructus Protect Against Diabetes-Induced Oxidative Stress, Inflammation, and Advanced Glycation End Product in Livers of Streptozotocin-Induced Diabetic Rats. J. Med. Food., 18, 337-344 (2015). |
428) |
Park M.H., Kim S.J., Jeong H.O., Moon K.M., Son S., Kim D.H., Kim H.R., Kim M.J., Yun H.Y., Chun P., Je N.K., Yokozawa T., Moon H.R., Chung H.Y.: Inhibition of melanogenesis by 2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2-methylpropanoic acid (MHY908). Arch. Pharm. Res., 38, 505-511 (2015). |
429) |
Ahn J.H., Choi J.W., Choi J.M., Maeda T., Fujii H., Yokozawa T., Cho E.J.: Protective role of oligonol from oxidative stress-induced inflammation in C6 glial cell. Nutr. Res. Pract., 9, 123-128 (2015). |
430) |
Lee C.M., Jung H.A., Oh S.H., Park C.H., Tanaka T., Yokozawa T., Choi J.S.: Kinetic and molecular docking studies of loganin and 7-O-galloyl-D-sedoheptulose from Corni Fructus as therapeutic agents for diabetic complications through inhibition of aldose reductase. Arch. Pharm. Res., 38, 1090-1098 (2015). |
431) |
Park C.H., Noh J.S., Tanaka T., Roh S.S., Lee J.C., Yokozawa T.: Polyphenol isolated from Corni Fructus, 7-O-galloyl-D-sedoheptulose, modulates advanced glycation endproduct-related pathway in type 2 diabetic db/db mice. Arch. Pharm. Res., 38, 1270-1280 (2015). |
432) |
Shin Y.O., Park C.H., Lee G.H., Yokozawa T., Roh S.S., Rhee M.H.: Heat-Processed Scutellariae Radix Enhances Anti-Inflammatory Effect against Lipopolysaccharide-Induced Acute Lung Injury in Mice via NF-κB Signaling. Evid. Based Complement. Alternat. Med., 2015, Article ID 456846, 12 pages (2015). |
433) |
Jung Y.R., Lee E.K., Kim D.H., Park C.H., Park M.H., Jeong H.O., Yokozawa T., Tanaka T., Im D.S., Kim N.D., Yu B.P., Mo S.H., Chung H.Y.: Upregulation of Collagen Expression via PPARβ/δ Activation in Aged Skin by Magnesium Lithospermate B from Salvia miltiorrhiza. J. Nat. Prod., 78, 2110-2115 (2015). |
434) |
Park S.K., Seong R.K., Kim J.A., Son S.J., Kim Y., Yokozawa T., Shin O.S.: Oligonol promotes anti-aging pathways via modulation of SIRT1-AMPK-Autophagy Pathway. Nutr. Res. Pract., 10, 3-10 (2016). |
435) |
Bak J., Je N.K., Chung H.Y., Yokozawa T., Yoon S., Moon J.O.: Oligonol Ameliorates CCl4-Induced Liver Injury in Rats via the NF-Kappa B and MAPK Signaling Pathways. Oxid. Med. Cell. Longev., 2016, Article ID 3935841, 12 pages (2016). |
436) |
Choi J.S., Bhakta H.K., Fujii H., Min B.S., Park C.H., Yokozawa T., Jung H.A.: Inhibitory evaluation of oligonol on α-glucosidase, protein tyrosine phosphatase 1B, cholinesterase, and β-secretase 1 related to diabetes and Alzheimer’s disease. Arch. Pharm. Res., 39, 409-420 (2016). |
437) |
Roh S.S., Kwon OJ., Yang J.H., Kim Y.S., Lee S.H., Jin J.S., Jeon Y.D., Yokozawa T., Kim H.J.: Allium hookeri root protects oxidative stress-induced inflammatory responses and β-cell damage in pancreas of streptozotocin-induced diabetic rats. BMC Complement. Altern. Med., 16, 63 (2016). |
438) |
Park C.H., Lee J.Y., Kim M.Y., Shin S.H., Roh S.S., Choi J.S., Chung H.Y., Song Y.O., Shin Y.S., Yokozawa T.: Oligonol, a low-molecular-weight polyphenol derived from lychee fruit, protects the pancreas from apoptosis and proliferation via oxidative stress in streptozotocin-induced diabetic rats. Food Funct., 7, 3056-3063 (2016). |
439) |
Bhakta H.K., Park C.H., Yokozawa T., Min B.S., Jung H.A., Choi J.S.: Kinetics and molecular docking studies of loganin, morroniside and 7-O-galloyl-D-sedoheptulose derived from Corni fructus as cholinesterase and β-secretase 1 inhibitors. Arch. Pharm. Res., 39, 794-805 (2016). |
440) |
Park C.H., Shin S.H., Lee E.K., Kim D.H., Kim M.J., Roh S.S., Yokozawa T., Chung H.Y.: Magnesium Lithospermate B from Salvia miltiorrhiza BUNGE Ameliorates Aging-Induced Renal Inflammation and Senescence via NADPH Oxidase-Mediated Reactive Oxygen Generation. Phytother. Res., 31, 721-728 (2017). |
441) |
Choi R.J., Roy A., Jung H.J., Ali M.Y., Min B.S., Park C.H., Yokozawa T., Fan T.P., Choi J.S., Jung H.A.: BACE1 molecular docking and anti-Alzheimer’s disease activities of ginsenosides. J. Ethnopharmacol., 190, 219-230 (2016).
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442) |
Bhakta H.K., Park C.H., Yokozawa T., Tanaka T., Jung H.A., Choi J.S.: Potential anti-cholinesterase and β-site amyloid precursor protein cleaving enzyme 1 inhibitory activities of cornuside and gallotannins from Cornus officinalis fruits. Arch. Pharm. Res., 40, 836-853 (2017).
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443) |
Park C.H., Shin M.R.., An B.K., Joh H.W., Lee J.C., Roh S.S., Yokozawa T.: Heat-Processed Scutellariae Radix Protects Hepatic Inflammation through the Amelioration of Oxidative Stress in Lipopolysaccharide-Induced Mice. Am. J. Chin. Med., 45, 1233-1252 (2017).
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444) |
Kim D.H., Paudel P., Yu T., Ngo T.M., Kim J.A., Jung H.A., Yokozawa T., Choi J.S.: Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B. Chem. Biol. Interact., 278, 65-73 (2017).
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445) |
Bhakta H.K., Paudel P., Fujii H., Sato A., Park C.H., Yokozawa T., Jung H.A., Choi J.S.: Oligonol promotes glucose uptake by modulating the insulin signaling pathway in insulin-resistant HepG2 cells via inhibiting protein tyrosine phosphatase 1B. Arch. Pharm. Res., 40, 1314-1327 (2017).
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