251) Yokozawa T., Kim H.Y., Nonaka G., Kosuna K.: Buckwheat Extract Inhibits Progression of Renal Failure. J. Agric. Food Chem., 50, 3341-3345 (2002).
252) Yokozawa T., Kashiwada Y., Hattori M., Chung H.Y.: Study on the Components of Luobuma with Peroxynitrite-Scavenging Activity. Biol. Pharm. Bull., 25, 748-752 (2002).
253) Yokozawa T., Nakagawa T., Kitani K.: Antioxidative Activity of Green Tea Polyphenol in Cholesterol-Fed Rats. J. Agric. Food Chem., 50, 3549-3552 (2002).
254) Yokozawa T., Chen C.P., Rhyu D.Y., Tanaka T., Park J.C., Kitani K.: Potential of Sanguiin H-6 against Oxidative Damage in Renal Mitochondria and Apoptosis Mediated by Peroxynitrite in vivo. Nephron, 92, 133-141 (2002).
255) Yokozawa T., Kim H.Y., Cho E.J.: Erythritol Attenuates the Diabetic Oxidative Stress through Modulating Glucose Metabolism and Lipid Peroxidation in Streptozotocin-Induced Diabetic Rats. J. Agric. Food Chem., 50, 5485-5489 (2002).
256) Yokozawa T., Kim H.Y., Cho E.J., Choi J.S., Chung H.Y.: Antioxidant Effects of Isorhamnetin 3,7-Di-O-β-D-glucopyranoside Isolated from Mustard Leaf (Brassica juncea) in Rats with Streptozotocin-Induced Diabetes. J. Agric. Food Chem., 50, 5490-5495 (2002).
257) Yokozawa T., Muto Y., Wakaki K., Kashiwagi H.: Site of Methylguanidine Production and Factors That Influence Production Levels. Nephron, 92, 356-362 (2002).
258) Nakagawa T., Yokozawa T.: Direct scavenging of nitric oxide and superoxide by green tea. Food Chem. Toxicol., 40, 1745-1750 (2002).
259) Rhyu D.Y., Yokozawa T., Cho E.J., Park J.C.: Prevention of Peroxynitrite-induced Renal Injury through Modulation of Peroxynitrite Production by the Chinese Prescription Wen-Pi-Tang. Free Radic. Res., 36, 1261-1269 (2002).
260) Nakagawa T., Yokozawa T., Oya T., Sasahara M., Terasawa K.: Evaluation of Keishi-bukuryo-gan in a diabetic nephropathy model by comparison with aminoguanidine, butylated hydroxytoluene and captopril. J. Trad. Med., 19, 200-208 (2002).
261) Yokozawa T., Kim H.Y., Cho E.J., Choi J.S.: Protective Effects of the BuOH Fraction from Mustard Leaf in a Renal Ischemia-Reperfusion Model. J. Nutr. Sci. Vitaminol., 48, 384-389 (2002).
262) Yokozawa T., Rhyu D.Y., Cho E.J., Aoyagi K.: Protective Activity of (-)-Epicatechin 3-O-gallate against Peroxynitrite-mediated Renal Damage. Free Radic. Res., 37, 561-571 (2003).
263) Yokozawa T., Ishida A., Cho E.J., Nakagawa T.: The effects of Coptidis Rhizoma extract on a hypercholesterolemic animal model. Phytomedicine, 10, 17-22 (2003).
264) Yokozawa T., Cho E.J., Nakagawa T.: Influence of Green Tea Polyphenol in Rats with Arginine-induced Renal Failure. J. Agric. Food Chem., 51, 2421-2425 (2003).
265) Nakagawa T., Yokozawa T., Terasawa K., Nakanishi K.: Therapeutic usefulness of Keishi-bukuryo-gan for diabetic nephropathy. J. Pharm. Pharmacol., 55, 219-227 (2003).
266) Yokozawa T., Rhyu D.Y., Chen C.P.: Protective Effects of Acanthopanax Radix Extract against Endotoxemia Induced by Lipopolysaccharide. Phytother. Res., 17, 353-357 (2003).
267) Kim H.Y., Yokozawa T., Cho E.J., Cheigh H.S., Choi J.S., Chung H.Y.: In Vitro and in Vivo Antioxidant Effects of Mustard Leaf (Brassica Juncea). Phytother. Res., 17, 465-471 (2003).
268) Yokozawa T., Kim H.Y., Cho E.J., Yamabe N., Choi J.S.: Protective Effects of Mustard Leaf (Brassica juncea) against Diabetic Oxidative Stress. J. Nutr. Sci. Vitaminol., 49, 87-93 (2003).
269) Cho E.J., Yokozawa T., Rhyu D.Y., Kim S.C., Shibahara N., Park J.C.: Study on the inhibitory effects of Korean medicinal plants and their main compounds on the 1,1-diphenyl-2-picrylhydrazyl radical. Phytomedinine, 10, 544-551 (2003).
270) Nakagawa T., Yokozawa T., Oowada S., Goto H., Shibahara N., Shimada Y., Terasawa K.: Amelioration of kidney damage in spontaneously diabetic WBN/Kob rats after treatment with Keishi-bukuryo-gan. J. Trad. Med., 20, 156-164 (2003).
271) Yokozawa T., Rhyu D.Y., Cho E.J.: Protection by the Chinese prescription Wen-Pi-Tang against renal tubular LLC-PK1 cell damage induced by 3-morpholinosydnonimine. J. Pharm. Pharmacol., 55, 1405-1412 (2003).
272) Soung D.Y., Rhee S.H., Kim J.S., Lee J.Y., Yang H.S., Choi J.S., Yokozawa T., Han Y.N., Chung H.Y.: Peroxynitrite scavenging activity of lithospermate B from Salvia miltiorrhiza. J. Pharm. Pharmacol., 55, 1427-1432 (2003).
273) Yokozawa T., Rhyu D.Y., Cho E.J., Satoh A., Hattori M.: Novel pharmacological potential of Rhei Rhizoma against peroxynitrite-induced oxidative renal injury. J. Trad. Med., 20, 235-242 (2003).
274) Cho E.J., Yokozawa T., Rhyu D.Y., Kim H.Y., Shibahara N., Park J.C.: The Inhibitory Effects of 12 Medicinal Plants and Their Component Compounds on Lipid Peroxidation. Am. J. Chin. Med., 31, 907-917 (2003).
275) Yokozawa T., Satoh A., Cho E.J.: Ginsenoside-Rd attenuates oxidative damage related to aging in senescence-accelerated mice. J. Pharm. Pharmacol., 56, 107-113 (2004).
276) Yokozawa T., Rhyu D.Y., Cho E.J.: (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. J. Pharm. Pharmacol., 56, 231-239 (2004).
277) Yokozawa T., Ishida A., Kashiwada Y., Cho E.J., Kim H.Y., Ikeshiro Y.: Coptidis Rhizoma: protective effects against peroxynitrite-induced oxidative damage and elucidation of its active components. J. Pharm. Pharmacol., 56, 547-556 (2004).
278) Satoh A., Yokozawa T., Cho E.J., Okamoto T., Sei Y.: Antioxidative effects related to the potential anti-aging properties of the Chinese prescription Kangen-karyu and Carthami Flos in senescence-accelerated mice. Arch. Gerontol. Geriatr., 39, 69-82 (2004).
279) Yokozawa T., Nakagawa T.: Inhibitory effects of Luobuma tea and its components against glucose-mediated protein damage. Food Chem. Toxicol., 42, 975-981 (2004).
280) Nakagawa T., Yokozawa T., Sano M., Takeuchi S., Kim M., Minamoto S.: Activity of (-)-Epigallocatechin 3-O-Gallate against Oxidative Stress in Rats with Adenine-Induced Renal Failure. J. Agric. Food Chem., 52, 2103-2107 (2004).
281) Satoh A., Yokozawa T., Tanaka T., Okamoto T., Sei Y.: The antioxidative activity of Kangen-karyu extract delays senescence of human lung fibroblasts. J. Trad. Med., 21, 87-93 (2004).
282) Yokozawa T., Yamabe N., Cho E.J., Nakagawa T., Oowada S.: A Study on the Effects to Diabetic Nephropathy of Hachimi-jio-gan in Rats. Nephron Exp. Nephrol., 97, e38-e48 (2004).
283) Kitani K., Yokozawa T., Osawa T.: Interventions in Aging and Age-Associated Pathologies by Means of Nutritional Approaches. Ann. N.Y. Acad. Sci., 1019, 424-426 (2004).
284) Cho E.J., Yokozawa T., Rhee S.H., Park K.Y.: The role of Coptidis Rhizoma extract in a renal ischemia-reperfusion model. Phytomedicine, 11, 576-584 (2004).
285) Yokozawa T., Sekiya M., Cho E.J., Kurokawa M., Shiraki K.: Effect of Wen-Pi-Tang extract on lung damage by influenza virus infection. Phytomedicine, 11, 625-632 (2004).
286) Jung H.A., Chung H.Y., Yokozawa T., Kim Y.C., Hyun S.K., Choi J.S.: Alaternin and Emodin with Hydroxyl Radical Inhibitory and/or Scavenging Activities and Hepatoprotective Activity on Tacrine-Induced Cytotoxicity in HepG2 Cells. Arch. Pharm. Res., 27, 947-953 (2004).
287) Yokoyama K., Shimada Y., Hori E., Nakagawa T., Takagi S., Sekiya N., Kouta K., Nishijo H., Yokozawa T., Terasawa K.: Effects of Choto-san and hooks and stems of Uncaria sinensis on antioxidant enzyme activities in the gerbil brain after transient forebrain ischemia. J. Ethnopharmacol., 95, 335-343 (2004).
288) Cho E.J., Yokozawa T., Kim H.Y., Shibahara N., Park J.C.: Rosa rugosa Attenuates Diabetic Oxidative Stress in Rats with Streptozotocin-Induced Diabetes. Am. J. Chin. Med., 32, 487-496 (2004).
289) Yokozawa T., Kim H.Y., Yamabe N.: Amelioration of Diabetic Nephropathy by Dried Rehmanniae Radix (Di Huang) Extract. Am. J. Chin. Med., 32, 829-839 (2004).
290) Kim H.Y., Yokozawa T., Nakagawa T., Sasaki S.: Protective effect of γ-aminobutyric acid against glycerol-induced acute renal failure in rats. Food Chem. Toxicol., 42, 2009-2014 (2004).
291) Kim H.Y., Yokozawa T., Cho E.J., Yamabe N.: Protective effects of the Chinese prescription Hachimi-jio-gan against diabetic oxidative stress. J. Pharm. Pharmacol., 56, 1299-1305 (2004).
292) Yokozawa T., Cho E.J., Rhyu D.Y., Shibahara N., Aoyagi K.: Glycyrrhizae Radix attenuates peroxynitrite-induced renal oxidative damage through Inhibition of protein nitration. Free Radic. Res., 39, 203-211 (2005).
293) Yokozawa T., Satoh A., Cho E.J., Kashiwada Y., Ikeshiro Y.: Protective role of Coptidis Rhizoma alkaloids against peroxynitrite-induced damage to renal tubular epithelial cells. J. Pharm. Pharmacol., 57, 367-374 (2005).
294) Kim Y.J., Yokozawa T., Chung H.Y.: Effects of energy restriction and fish oil supplementation on renal guanidino levels and antioxidant defences in aged lupus-prone B/W mice. Br. J. Nutr., 93, 835-844 (2005).
295) Yokozawa T., Nakagawa T., Oya T., Okubo T., Juneja L.R.: Green tea polyphenols and dietary fibre protect against kidney damage in rats with diabetic nephropathy. J. Pharm. Pharmacol., 57, 773-780 (2005).
296) Piao X.L., Kim H.Y., Yokozawa T., Lee Y.A., Piao X.S., Cho E.J.: Protective Effects of Broccoli (Brassica oleracea) and Its Active Components against Radical-Induced Oxidative Damage. J. Nutr. Sci. Vitaminol., 51, 142-147 (2005).
297) Kim H.Y., Yokozawa T., Cho E.J.: Mustard Leaf Suppresses Nitric Oxide Synthesis by Mouse Macrophages. J. Nutr. Sci. Vitaminol., 51, 200-203 (2005).
298) Nakagawa T., Yokozawa T., Yamabe N., Rhyu D.Y., Goto H., Shimada Y., Shibahara N.: Long-term treatment with Hachimi-jio-gan attenuates kidney damage in spontaneously diabetic WBN/Kob rats. J. Pharm. Pharmacol., 57, 1205-1212 (2005).
299) Nakagawa T., Yokozawa T., Kim Y.A., Kang K.S., Tanaka T.: Activity of Wen-Pi-Tang, and Purified Constituents of Rhei Rhizoma and Glycyrrhizae Radix against Glucose-Mediated Protein Damage. Am. J. Chin. Med., 33, 817-829 (2005).

300)Nakagawa T., Yokozawa T., Kim H.J., Shibahara N.: Protective Effects of γ-Aminobutyric Acid in Rats with Streptozotocin-Induced Diabetes. J. Nutr. Sci. Vitaminol., 51, 278-282 (2005).